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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42f7ac8c485708d8e2f6485f06365226986a56d7a2c21910304ab08acfa41d7' 
  AND token = 'F2HibuCaOlngUYiTL51DQJRHwL7b/dXEfV1B9NL0dDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}