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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3614f036199222087759336fe123d2aafea376997407919304a6d09c316c82' 
  AND token = 'MMfBoDk8M3bW6rYkgrQgm+JCfivqb42bRZg+tTy7Gzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}