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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77d1291c632cba49ac9b38528fa4d4ab13fdd7b80fbb502b72ec997aac4f6bdd' 
  AND token = '74bYm1lY3+3xA7k68rhFQV7UmCL6pNozGw9v1v+buMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}