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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287d8ce9608b6ea7fa446ced701927880703f0bf0122f7f1a966768399d6af03' 
  AND token = 'LoioFE4gge0/POeHb5r101PWfR7ErEgvc7NnnPlj2c0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}