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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b331ee2963eb1a04044aa043d4c02c9a46255031754f8f1f981b14141a27a82' 
  AND token = 'JgUdYB+hI+3CxF73UoiFCLcF6Ywjlz5mjeSoe3s5Oi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}