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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0247fa3d94c5120cd5e0777e174541e0b94d9c2e60751b63b3d1d2604226c3' 
  AND token = 'nynI+FEKIbLQ81aexYGracWWSHKt1YyylZa/ibyDHNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}