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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ca2eaa4cb281d54ca74be7d68a897d600b5b34c4ca146152e3697f7d9a9632' 
  AND token = 'v+KVnxaqr3rywwaoCzJIwyMSF7PoERNmdC1kuNzClKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}