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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641c8f237bf876fcc79bca55e2d032eb00180d33d17002987d0cbff8c3bab18c' 
  AND token = '8KlwrDm2G/eUGYfi2uu0gmhFDHpH5qRYJPQOJCXSr2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}