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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca8c458c1fbc7aece38ec406562ac2738e73f83a8102297f7e7dc69b86e7fe0' 
  AND token = 'aXtcJ3JdWIU9RvMRmOrwWL4QBSCBM1hxwEC8Is0gpU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}