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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d1404952af1fdc78019a648402b16802795d5894a95e78deca3a1bf6e9a51b' 
  AND token = 'Aw5gBXck+61dmXwWkqA6QFtlS/EnnYiFRSgRy8oHdyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}