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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec06573ab75f69d35ab754d443ecc8b0875d2eb1dd275e46970ada06982eea19' 
  AND token = 'PlXXb7HmdqSf++rYx3POOYzZkt3iX0UakKWKPByIAk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}