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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f54ffde90a1817ef8411e2e24f2eda563f9b0963d88899d69e704dc9e723c74' 
  AND token = 's0pp6PoOa8S329phSBG//TaREQxfEJnTx7rJ0dPrx9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}