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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fded3cc0f92a80d35a5a5b53956a31a483a0f52fad2d961a34bc39809ce6e5a9' 
  AND token = 'lHleX3SkoIUzlQ7vjGqMDFgcMxZ/uBw1mQrvpe3OGow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}