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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87757c639b17db25f1447a27dbb3ad5a4bb82f4d5487890964773de9a34ea944' 
  AND token = 'OrZyLSD7wIas4XuBVkS7EXxRTd4TI9DtZA+Tvu0uZKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}