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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32c4855869003f3371014cac28bf02d8e58e8da4cdc1c9ef85f6edb298b3309b' 
  AND token = 'KdS/OhfcpXcabA0/5x/8mrAIsC94LlA3xGsysgL8CxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}