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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6889dad73b3ab90e6d7773e53da8e10314a93c1b2026b20b6e15fb7955da5077' 
  AND token = 'uzeY2OC8Z6SqkOmOvvYAyzNG+DufjENd2tjqjIePqt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}