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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4108460f730d51855707f53a3a13c06e569c87c64773e4e61e739c9527d16f7' 
  AND token = 'LZ1/mGxF2cE89ih+YvY1aYoIa0yeQf2qFdhf15DK75U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}