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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '943ce6a5a76afc663b75a7297c1ad163723ed6fcb10e7e7e117a74dc2ad12ee8' 
  AND token = 'wjWCmc+80POmGbtzy5f94Gdc5NJgRGFynVUw5ydTQAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}