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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73de4724f619112ebb4b40c9865c89f291fed9898793f51ae14829ecb59a6310' 
  AND token = 'XJ7/mQY0v4zMEJV79CDOuPiVv0L5SwpSURozEOyWBAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}