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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45ea0281c07fc1c1c8cce6ed6f8a2089aa96d70c686ee848526e7032c01b1f8' 
  AND token = 'sbbo8gqiXlsaOaDivPL/ZnxEZS+2EHptdEccdxGuaDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}