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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d8397b7a07e78734523273281ac522f26d0aa24be0b0d6de72a1911f78de3e' 
  AND token = 'rppSvOjp4w6V3jqWBSSRC9AntXJZDAtM3wRbkj6sTt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}