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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a5126f49c9500364c62ad36385faffa81d072e97cded6df5aab1af0426195d' 
  AND token = '3Riy0AFZYyUVMdvChFFhJ1Nk7pHQmeBGiC8r9HgCWT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}