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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e84e6091b25ff81f84d02e930523c2f2b49319b86b4cc0b659818ccc06e5d488' 
  AND token = 'MVrC4kzYk+QH7NCiS499LrZd90AyWsJ33crp9tVynso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}