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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6409ad2878c9f8f64859e4fa4aaa1603e0582597e483ed10023fa6a5e1b322f' 
  AND token = 'l5OvLBA6OxtxUP06TD5QrFf6pDRVjO/E9L//Z0VzN4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}