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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b292db56ebe5c1eef9b0d66148af5a2aa4aa858459bec47970fce387a3f96372' 
  AND token = 'QHxAQnXLej/9COG/pjdwNdB8DOPs7NHx4bi7CpVAj90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}