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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ab3b5b8308f8597944d89038f62a0424710e39829d7c68f74ce781242277c5' 
  AND token = 'Ypnn9T/J816HENwRVSO4QqbMsXWoBc2g0VQH236oQeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}