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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e682b546d287971a821ca4c658a3fad5427e02b3957d54755e5c0c5564947e64' 
  AND token = 'tFiRP7DEIzdtOxHHN+V/rE/Aar3UpyLwJSTS1M4bV3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}