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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4074b1c1dd22c37f18fcd740f8f17266dda8a965483bc210d064d4aaf426f29' 
  AND token = 'R033I1fGElpEjUUy0/Tsx+ZGMY8hRhlGcTBem0piuTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}