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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '920051f4247e96b342a58fb89808d460f970f72a79f1dbb2d301568f98f1c1cd' 
  AND token = 'pynJMvrkrIRPYWI8jlPgQbnRPMZv6LYykLv6dlox5cM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}