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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b88c35e424923f18df87406406da7c8d3595e9df784f573d8bb48c8b46b9e50' 
  AND token = 'tMSvp1wQ/FU7xcAc1RNLGrrI4LsGDWw5OdybUU+MGOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}