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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46b27843563f597cde0b8a0a83e631180179e0cc63f2a35d9f547a6707831d3' 
  AND token = 'pef46d3NiDuUW/DwM13IUC2DdpRSmFxrGsTwpzzY8lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}