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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '563d813ff8b6b5b5f6562b0f6df5c6d7e7ca3fe399e030990c849fb54f34ac29' 
  AND token = '1Bqy4/gRPb1qEkgu2PnZcsK+PCydwQcgKUP6ZoeWhMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}