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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51fc20d680a344f8cbc428309bb39d088b43f3b7beb577d8c3928cd43dc0bb7' 
  AND token = '2Hg/WlxzjIGz+xRqJHKEZb4cey6+xDoJkIUu9sLojpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}