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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38e443b4d75b27106da8f4084d14c0b660cd99e3c3b42f80e33488da0d4284d7' 
  AND token = 'VeMfCCeAT4NCmVWnLzBYfcG8Hm+EsTRYUt71wznleuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}