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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5333632b4c615fa32e59d06a1527e0026cc928aaf3aa274fa70a89f0f5d89b9f' 
  AND token = 'VqaWBMrOsIevwRV54rxHNWf58tFtmhr8Nc1vr9H4ASU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}