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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500626bbf595489fc50259df7c3ee4b6270cf994bb8bab2a856f4f1ba2e326b9' 
  AND token = 'dOPCVyh6MtddRITqqqB4l+a3jeckhkRNddGqZceGMNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}