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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed8c2e3809f3195d1a12c48e0fd84dd06b9f6b7a94732e86be3e289911f8c27' 
  AND token = 'T6HOiuM6QYvwcfnsYMIXtyVC0iNm1ydOdZk3Tnp/WXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}