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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb39185d49b64a8779ce2e949d901c94bba8fdffd23143de360f0095fdec9c1' 
  AND token = 'AFOeF5Sk9x87Do5q5UYD3u0TZXhT8GvtyUed5Dj7Z64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}