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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b183ad2f9985e7bcea02081998bdb03a47f0abc747e5b6752ca603a33dded310' 
  AND token = 'k8Zgp1r/ysjMiBq3QckKAoUlvaZ1cOK1LSflrM4zVxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}