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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c6d52a30a99394350cb7aff46f7f9530f46eecbd78997d77dd7570c65c79c2' 
  AND token = 'SlsHo+VmZfZdRUR0t+W6cwB7smyeuryVivnipTsp5wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}