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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbdcb6035c4433dc4763e64c9b8107bc5828f3c4e4f1e3d9b080209022f03ed6' 
  AND token = 'rFKkby5NieiSPOocdcoZU1lxOm4RrCmQBumIFnEFKSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}