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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '002fbc400e5d98e4d1605509b12f55f1d8f22459350fbc79f6b0a900f57dbcc3' 
  AND token = 'Z7FSX/4RnRIfTK/DDsDWmcKCxG7Qi5gWFr4VEFeuxUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}