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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbad63369aeaf5f2d4ea724a5465b29999ad2b36c10022f158f80419aeb600fd' 
  AND token = 'oqT3eegkvU1hvF1afZoGIM5olSqeaaEwd3DzftiIGYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}