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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7ffbab0893b2363c62fad019e42dcee8e01d76f39a6d6331d5a1d6940048e7' 
  AND token = 'HmVSjdX+WTR/z5I1YYh4kGQtEWTbeA2pp3hBBMRjATY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}