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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcfd28198bb58764a3fe9568905a49ffa3aadaf2611c111a041b1c405b150de1' 
  AND token = '+dYh1ckhBLQ1i++nT3w3O+FXNso9VHenMK2dAEp7iPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}