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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25b242a7851c90abf73c59880b04956f416b3c72e18e7f49c5e78eada24f601' 
  AND token = 'zH1se71vVjwFWB/70x/fUah69TayQIjMjaEn/JSOE3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}