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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab55186fbf6cdd804d6e0f3d15f34c1431f1991be69e57aa519f664af628e53' 
  AND token = 'uUAtEXrZyEuM4YpvddaNNP0Sr332YbGjDnqi0+KUxHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}