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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '905f5c15c949a468f51f334dd9b57812ffb0ac7bca5c48d3d9b61e127c578cce' 
  AND token = 'mqZ/M9xgxjemlg0tf3gY5uYAwyeYTZVppKa3Z4uyg1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}