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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dcdd87ce2e44b112ddebaf6dfe26334528d6a2c5a64edc285105f7799533a7' 
  AND token = 'vyXdjCdc4AHmB2oE4EGLWSwe1NtEdncNPWjn58mgWW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}