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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '834d2316bbca5036b3c0bbe9bacdc320193a13a28d1f7f505b6186cfe7321704' 
  AND token = '2cSDKJXFNLC2s0t9+8UWd+gZw3wtyFrQBCBrFc/IxLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}